Sophora Japonica Extract Quercetin Rutin Powder 95% quercetin

Rutin is extracted from dried buds of Sophorae Japonica. Pure rutin is yellow or yellow-green colored needle-shaped crystal. Rutin is a flavonol glycoside comprised of the quercetin and the disaccharide rutinose. Rutin is a powerful antioxidant. It helps the body utilize vitamin C, supports blood vessel integrity, and promotes a healthy inflammation response. It is also used in food industry as a pigment.
Rutin, which is also known as vitamin P and rutoside, is a bioflavonoid that's found in certain foods, including apples, figs, most citrus fruits, buckwheat and green tea. Like all flavonoids, it has powerful antioxidant and anti-inflammatory effects. It's used as medicine to strengthen blood vessels, improve blood circulation, lower cholesterol and relieve arthritis symptoms.
Rutin is also known for its potential ability to promote the production of collagen and help the body to use vitamin C properly. The name of the flavonoid comes from the name of the plant Ruta graveolens, which also contains this phytonutrient. Chemically, rutin is a glycoside that comprises flavonolic aglycone quercetin, along with disaccharide rutinose.
Rutin can be used as edible antioxidants and nutritional enhancers.
Rutin is a widely-sourced flavonoid, mainly found in the flower buds (glutinous rice), fruits (horns) of the legumes (Sophora

japonica L.), and the whole grass of Rutagraveolenslens L. Peach and so on.

TEST	EP8	RESULTS	Test Method
Appearance	Light greenish yellow powder	Complies	Visual
Identification	B.IR absorbance	Matching	IR
	A.UV absorbance	Matching	UV
	C.TLC Examination	Matching	TLC
	D.Color reaction with Zn	Matching	Visual
Particle size	95% pass through sieve 80mesh	Complies	US Screen
Residual solvents	≤2.0%	0.06%	HPGC
Light absorbing impurities	Abs≤0.10 between 450-480nm	0.05	UV
Susbtance insoluble in methanol	≤3.0%	0.80%	CP2010
Impurity
A.Isoquercetin	≤2.0%	0.41%	HPLC
B.Kaempferol3-Rutinoside	≤2.0%	1.45%	HPLC
C.Quercetin	≤2.0%	0.04%	HPLC
Total Impurity	≤4.0%	3.31%	HPLC
Bulk density	≥0.30gm/cc	0.37gm/cc	CP2010
Tapped density	≥0.50gm/cc	0.56gm/cc	CP2010
Residual Solvents Methanol	≤0.3%	<0.3%	GC
Heavy metals	≤10ppm	<10ppm	Visual Colorimetry
Arsenic	≤1ppm	<1ppm	AAS
Mercury	≤0.1ppm	<0.1ppm	AAS
Cadmium	≤1ppm	<1ppm	AAS
Lead	≤3ppm	<3ppm	AAS
Ash	≤0.10%	0.08%	CP2010
Loss on drying	7.5%-9.5%	8.60%	105ºC/3h
Assay(on dry basis)	95.0%-101.0%	99.94%	UV
Microbiological test:
Total plate count	≤1000cfu/g	100cfu/g	AOAC966.23
Mildew&Yeast	≤100cfu/g	20cfu/g	FDABAM8th
E.Coli	Negative	Negative	FDABAM8th
Salmonella	Negative	Negative	FDABAM8th
Coliforms	≤10cfu/g	<10cfu/g	AOAC911.14
Enterobacteria	Negative	Negative	FDABAM8th
Resticide Screen	Meets the requirements of EP 8.
GMO/BSE Status	Not genetically modified organism .Free of BSE
Storage	Store in tight containers,in a cool dry area.

Function:

Rutin is not an especially large flavonoid, but specific parts of its molecule interact with different systems in the body, such
as the brain, heart, or blood vessels.
For example, rutin contains two bound sugar molecules, which enhance its antioxidant effects on the brain.
Overall, rutin acts by:
1. Protecting brain cells from damage
2.Blocking inflammatory enzymes (phospholipase A2), similar to corticosteroids but without the side effects
3. Reducing oxidative stress and free radicals
4.Safely lowering high blood pressure, affecting similar pathways as drugs used for high blood pressure (blocks ACE)
5.Boosting acetylcholine (by clocking the enzyme that degrades it, AChE)
6. Binding to and neutralizing toxic compounds that build up in the body if exposed to radiation
7.Relaxing blood vessels

Application:
As all flavonoids, rutin is an antioxidant. It's one of the most important and well-researched flavonoids. It protects the cells and has anti-inflammatory, cancer-fighting potential. By its widespread action, rutin can protect the heart, liver, brain, and bones.
 
1. Rutin can be used as edible antioxidants and nutritional enhancers.

2. Rutin has vitamin P-like action and anti-inflammatory effect, can reduce inflammation caused by mustard oil on animal eyes or skin, has anti-viral effect, and has the largest vesicular stomatitis virus at a concentration of 200 μg·ml-1 Inhibition. It has strong antioxidant properties, and the addition of rutin to the lysosome-rich homogenate can inhibit the formation of lipid-like peroxides. It can strongly absorb ultraviolet rays at 280-335 nm and can be used for sunscreen whitening cosmetics.
 
3. Rutin has the functions of maintaining vascular resistance, reducing its permeability, and reducing fragility. It can be used to prevent diseases such as cerebral hemorrhage, hypertension, retinal hemorrhage, purpura and acute hemorrhagic nephritis.

4.Pharmaceuticals Function: Anti-free radical action, Anti-lipid peroxidation, Antagonistic effect of platelet activating factor, Anti-acute pancreatitis